BDBM50053566 4-{3-[7-(4,5-Dihydro-thiazol-2-yl)-5-furan-3-yl-naphthalen-2-yloxymethyl]-phenyl}-tetrahydro-pyran-4-ol::CHEMBL128300

SMILES OC1(CCOCC1)c1cccc(COc2ccc3c(cc(cc3c2)C2=NCCS2)-c2ccoc2)c1

InChI Key InChIKey=AFWQLFMODNHFNK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50053566   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50053566(4-{3-[7-(4,5-Dihydro-thiazol-2-yl)-5-furan-3-yl-na...)
Affinity DataIC50:  50nMAssay Description:Potency to inhibit oxidation of arachidonic acid by recombinant human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed